Sampling and pharmacokinetics of skin interstitial fluid for therapeutically monitored drugs

To guide therapeutic decision making, the pharmacokinetics (PK) of certain toxic drugs are typically studied in blood. A drug’s blood concentration is thus acting as a surrogate for its target site concentration. However, a drug’s target is often extravascular and measuring tissue concentrations wou...

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Bibliographic Details
Main Author: Schmitt, Veronika
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/56176

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