Characterization of the mechanisms by which Carbonic Anhydrase IX facilitates tumour growth and metastasis
The presence of hypoxic microenvironments in solid tumours is a marker of poor prognosis in numerous cancer types, including breast cancer; the second leading cause of cancer-related death. Hypoxia results in an adaptive response in tumour cells through the activation of the transcription factor Hyp...
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| Language: | English |
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University of British Columbia
2015
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| Online Access: | http://hdl.handle.net/2429/52795 |