Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression

DNA methylation is thought to play an important role in the regulation of mammalian gene expression. Part of the evidence for this role is the observation that lack of CpG island methylation in gene promoters is associated with high transcriptional activity. However, CpG island methylation level onl...

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Bibliographic Details
Main Author: Edgar, Rachel
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/50302

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