Strategies employed by enzymes to generate and stabilize radical intermediates : an examination of adenosylcobalamin- and pyridoxal 5'-phosphate-dependent ornithine 4,5-aminomutase
Enzymes that employ radical-based chemistry are able to catalyze a diverse array of energetically and chemically challenging reactions. Notably, their ability to break C–C, C–N, and C–H bonds makes them appealing targets for the development of biocatalysts. The research herein aims to investigate th...
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| Language: | English |
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University of British Columbia
2014
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| Online Access: | http://hdl.handle.net/2429/49976 |