Characterization of alternative reading frame selection by a viral internal ribosome entry site

Dicistroviruses possess a positive-sense, monopartite single-strand RNA genome that encodes two open reading frames containing the nonstructural and structural polyproteins (ORF1 and ORF2) separated by the intergenic region (IGR) internal ribosome entry site (IRES). Translation of each ORF is dir...

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Bibliographic Details
Main Author: Ren, Qian
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/48576