Deep sequencing of HIV-1 envelope determines coreceptor usage and predicts virologic responses to antiretroviral treatment with CCR5 antagonist medication
Next-generation sequencing can be used to genotype an array of HIV variants within clinical specimens, in a process referred to as deep sequencing. When directed at the gene for HIV envelope, this approach can be used to generate a high-sensitivity overview of the viral tropism of the HIV quasispeci...
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| Language: | English |
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University of British Columbia
2014
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| Online Access: | http://hdl.handle.net/2429/46764 |