DNA:RNA hybrid genome-wide profiling and links to genomic instability

DNA:RNA hybrid formation is emerging as a significant cause of genomic instability in biological systems ranging from bacteria to mammals. However, the scope of cellular pathways that prevent DNA:RNA hybrids and the genomic loci prone to hybrid formation are unclear. In Saccharomyces cerevisiae, DNA...

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Bibliographic Details
Main Author: Chan, Yujia Alina
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/46327