Reciprocal regulation of glutamine metabolism and reactive oxygen species

Reactive oxygen species (ROS) are byproducts of normal cellular processes. While low or moderate levels of ROS promote and sustain oncogenic properties of cancer cells, excessive amounts are detrimental. Cancer cells counterbalance increased ROS production by engaging ROS-scavenging systems, which h...

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Bibliographic Details
Main Author: Cetinbas, Naniye
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/45714