The discovery of functional single nucleotide polymorphisms and novel gene mechanisms that may explain mortality and organ dysfunction in septic shock
Septic shock (sepsis accompanied by cardiovascular failure) is an extreme manifestation of the host inflammatory response to severe infection. Tumor necrosis factor alpha (TNFα) super family induced nuclear factor kappa B (NF-κB) signaling pathways play a critical role in the pathophysiology of the...
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| Language: | English |
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University of British Columbia
2013
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| Online Access: | http://hdl.handle.net/2429/45337 |