Characterizing the immunomodulatory effects of the antioxidant TEMPOL in a model of multiple sclerosis

Background: Reactive oxygen and nitrogen species are implicated in inflammatory-mediated damage to the central nervous system in multiple sclerosis (MS) and an animal model of the disease, experimental autoimmune encephalomyelitis (EAE). We have shown that oral administration of the antioxidant TEMP...

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Bibliographic Details
Main Author: Neil, Sarah Elizabeth
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/45335