Developmental consequences of imprinted transcription at the Mest locus

The Mest locus is regulated by genomic imprinting in mammals and only the paternally inherited allele is expressed. A targeted mutation at this locus revealed that it plays an important role in the regulation of embryonic growth and adult behavior. The Mest locus is located in a conserved imprinted...

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Bibliographic Details
Main Author: MacIsaac, Julia Lynn
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44537

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