Evolutionarily conserved synthetic lethal interaction networks reveal targets for anticancer therapeutic development
Cancer is a multigenic disease. The genetic distinctness of cancer cells offers a weakness that can be exploited: for example, nearly all cancers carry mutations in processes relating to the maintenance of genomic stability. As this is an essential process, this presents a weakness that can be lever...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/43505 |