Studies in experimental hypertension
The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated. 1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt. 2. Estrogen overdosage produced hypertension in rats. Castrate animals were mo...
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ndltd-UBC-oai-circle.library.ubc.ca-2429-416062018-01-05T17:50:44Z Studies in experimental hypertension Salter, James Morley Blood pressure The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated. 1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt. 2. Estrogen overdosage produced hypertension in rats. Castrate animals were more sensitive to the effects of estrogen. Estrogen overdosage aggravated experimental hypertension induced by nutritional choline deficiency. 3. A period of nutritional choline deficiency was followed by hypertension. Desoxycorticosterone accelerated the development of hypertension in choline deficient animals. 4. Hypertension developed in rats 2 months after a prolonged period of inanition. 5. Antihistamine was found to induce profound variations in the blood pressure of male rats. 6. Rats pre-treated with desoxycorticosterone acetate showed a greater pressor response to adrenaline than normal intact rats. 7. Desoxycorticosterone and antihistamine were found to facilitate the occurrence of the Trueta shunt. Science, Faculty of Botany, Department of Zoology, Department of Graduate 2012-03-20T20:59:33Z 2012-03-20T20:59:33Z 1950 Text Thesis/Dissertation http://hdl.handle.net/2429/41606 eng For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use. University of British Columbia |
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NDLTD |
language |
English |
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NDLTD |
topic |
Blood pressure |
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Blood pressure Salter, James Morley Studies in experimental hypertension |
description |
The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated.
1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt.
2. Estrogen overdosage produced hypertension in rats. Castrate animals were more sensitive to the effects of estrogen. Estrogen overdosage aggravated experimental hypertension induced by nutritional choline deficiency.
3. A period of nutritional choline deficiency was followed by hypertension. Desoxycorticosterone accelerated the development of hypertension in choline deficient animals.
4. Hypertension developed in rats 2 months after a prolonged
period of inanition.
5. Antihistamine was found to induce profound variations in the blood pressure of male rats.
6. Rats pre-treated with desoxycorticosterone acetate showed a greater pressor response to adrenaline than normal intact rats.
7. Desoxycorticosterone and antihistamine were found to
facilitate the occurrence of the Trueta shunt. === Science, Faculty of === Botany, Department of === Zoology, Department of === Graduate |
author |
Salter, James Morley |
author_facet |
Salter, James Morley |
author_sort |
Salter, James Morley |
title |
Studies in experimental hypertension |
title_short |
Studies in experimental hypertension |
title_full |
Studies in experimental hypertension |
title_fullStr |
Studies in experimental hypertension |
title_full_unstemmed |
Studies in experimental hypertension |
title_sort |
studies in experimental hypertension |
publisher |
University of British Columbia |
publishDate |
2012 |
url |
http://hdl.handle.net/2429/41606 |
work_keys_str_mv |
AT salterjamesmorley studiesinexperimentalhypertension |
_version_ |
1718597014728474624 |