Studies in experimental hypertension

The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated. 1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt. 2. Estrogen overdosage produced hypertension in rats. Castrate animals were mo...

Full description

Bibliographic Details
Main Author: Salter, James Morley
Language:English
Published: University of British Columbia 2012
Subjects:
Online Access:http://hdl.handle.net/2429/41606
id ndltd-UBC-oai-circle.library.ubc.ca-2429-41606
record_format oai_dc
spelling ndltd-UBC-oai-circle.library.ubc.ca-2429-416062018-01-05T17:50:44Z Studies in experimental hypertension Salter, James Morley Blood pressure The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated. 1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt. 2. Estrogen overdosage produced hypertension in rats. Castrate animals were more sensitive to the effects of estrogen. Estrogen overdosage aggravated experimental hypertension induced by nutritional choline deficiency. 3. A period of nutritional choline deficiency was followed by hypertension. Desoxycorticosterone accelerated the development of hypertension in choline deficient animals. 4. Hypertension developed in rats 2 months after a prolonged period of inanition. 5. Antihistamine was found to induce profound variations in the blood pressure of male rats. 6. Rats pre-treated with desoxycorticosterone acetate showed a greater pressor response to adrenaline than normal intact rats. 7. Desoxycorticosterone and antihistamine were found to facilitate the occurrence of the Trueta shunt. Science, Faculty of Botany, Department of Zoology, Department of Graduate 2012-03-20T20:59:33Z 2012-03-20T20:59:33Z 1950 Text Thesis/Dissertation http://hdl.handle.net/2429/41606 eng For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use. University of British Columbia
collection NDLTD
language English
sources NDLTD
topic Blood pressure
spellingShingle Blood pressure
Salter, James Morley
Studies in experimental hypertension
description The effects of dietary and hormonal factors upon the blood pressure of male Wistar rats were investigated. 1. Desoxycorticosterone acetate was found to increase the blood pressure in the presence of excess dietary salt. 2. Estrogen overdosage produced hypertension in rats. Castrate animals were more sensitive to the effects of estrogen. Estrogen overdosage aggravated experimental hypertension induced by nutritional choline deficiency. 3. A period of nutritional choline deficiency was followed by hypertension. Desoxycorticosterone accelerated the development of hypertension in choline deficient animals. 4. Hypertension developed in rats 2 months after a prolonged period of inanition. 5. Antihistamine was found to induce profound variations in the blood pressure of male rats. 6. Rats pre-treated with desoxycorticosterone acetate showed a greater pressor response to adrenaline than normal intact rats. 7. Desoxycorticosterone and antihistamine were found to facilitate the occurrence of the Trueta shunt. === Science, Faculty of === Botany, Department of === Zoology, Department of === Graduate
author Salter, James Morley
author_facet Salter, James Morley
author_sort Salter, James Morley
title Studies in experimental hypertension
title_short Studies in experimental hypertension
title_full Studies in experimental hypertension
title_fullStr Studies in experimental hypertension
title_full_unstemmed Studies in experimental hypertension
title_sort studies in experimental hypertension
publisher University of British Columbia
publishDate 2012
url http://hdl.handle.net/2429/41606
work_keys_str_mv AT salterjamesmorley studiesinexperimentalhypertension
_version_ 1718597014728474624