Isolation and structure elucidation of bioactive marine natural products

Clionamines A-D (2.6-2.9) are new aminosteroids isolated from South African specimens of the sponge Cliona celata. All four compounds (2.6-2.9) are activators of autophagy in MCF-7 cells. Autophagy is a catabolic process that plays an important role in maintaining cellular homeostasis. Autophagy is...

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Bibliographic Details
Main Author: Daoust, Julie
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/37536