Application of oxo reaction to two carbohydrate derivatives nucleoside synthesis
Hydroformylation of 5,6-anhydro-1,2-0-isopropylidene-α-D-glucofuranose (XXIV) with carbon monoxide (70 atm.) and hydrogen (70 atm.) at a temperature of 100-105° C. gave 6-deoxy-1,2-0-i sopropylidene-α-D-gluco-heptodialdo-1,4-furanose-3,7-pyranose (XXV) in 78% yield. Minor quantities of the rearrange...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/36596 |