Small molecules as modulators of mitotic arrest and senescence in cancer
Manipulation of the cell cycle is an extensively used and promising strategy for cancer therapy. To identify novel cell cycle modulators, automated fluorescence microscopy assays were designed and used to screen chemical libraries for modulators of mitotic arrest and senescence. 8-azaguanine, IC 261...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/33801 |