Pathogenesis of neurofibromatosis 1 associated neurofibromas
Neurofibromatosis 1 (NF1) is an autosomal dominant disease. Neurofibromas, benign tumours that develop from peripheral nerves, are a hallmark feature of NF1. Malignant peripheral nerve sheath tumours (MPNSTs) are one of the leading causes of death in people with NF1. Clinical evidence suggests that...
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Language: | English |
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University of British Columbia
2011
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Online Access: | http://hdl.handle.net/2429/31176 |