Pathogenesis of neurofibromatosis 1 associated neurofibromas

Neurofibromatosis 1 (NF1) is an autosomal dominant disease. Neurofibromas, benign tumours that develop from peripheral nerves, are a hallmark feature of NF1. Malignant peripheral nerve sheath tumours (MPNSTs) are one of the leading causes of death in people with NF1. Clinical evidence suggests that...

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Bibliographic Details
Main Author: Tucker, Tracy
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31176