Novel peptide-derived cathepsin K inhibitors from Streptomyces
Human cathepsin K is a cysteine protease that is a member of the papain superfamily. It is selectively expressed in osteoclasts where it is involved in collagen type I degradation during bone resorption. As such, cathepsin K represents a potential drug target for the treatment of metabolic bone dise...
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Language: | English |
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University of British Columbia
2010
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Online Access: | http://hdl.handle.net/2429/30305 |
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