Novel peptide-derived cathepsin K inhibitors from Streptomyces
Human cathepsin K is a cysteine protease that is a member of the papain superfamily. It is selectively expressed in osteoclasts where it is involved in collagen type I degradation during bone resorption. As such, cathepsin K represents a potential drug target for the treatment of metabolic bone dise...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2010
|
| Online Access: | http://hdl.handle.net/2429/30305 |