Brefeldin A arrests the maturation and egress of herpes simplex virus particles during infection

Herpes Simplex Virus (HSV) requires the host cell secretory apparatus for the maturation and egress of newly synthesized viral particles. Not only do viral glycoproteins rely on the host ER and Golgi compartments for their proper processing, it is believed that enveloped particles are transported th...

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Bibliographic Details
Main Author: Cheung, Peter
Language:English
Published: University of British Columbia 2010
Subjects:
Online Access:http://hdl.handle.net/2429/29798