Conformationally controlled reactions in 14-membered macrolides
The conformationally controlled reactions of macrolides 42, 43, 72 and 74 were investigated. Treatment of these 14-membered lactones with hydride reducing agents and organocopper reagents led to diastereoselective product formation. The product distributions could be rationalized using low energy st...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/28844 |