Role of PKMz in morphological and synaptic development of optic tectal neurons in Xenopus laevis tadpoles in vivo

PKMz (Protein Kinase M zeta) is a recently identified isoform of Protein Kinase C. It is persistently active upon synthesis because its sequence resembles the catalytic domain of PKC zeta but lacks the auto-inhibitory regulatory domain. Previous studies found that PKMz is critical for LTP maintenanc...

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Bibliographic Details
Main Author: Liu, Xuefeng
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/28820