Investigating the role of the inhibitor of apoptosis protein, Apollon, in the regulation of autophagy in breast cancer cells

Macroautophagy (autophagy) is a lysosomal process for degrading cytoplasmic proteins and organelles for maintenance of homeostasis as well as for bioenergetic and biosynthetic needs. During nutrient deprivation and chemotherapy, both tumour-related stresses, autophagy is upregulated. The molecules a...

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Bibliographic Details
Main Author: Hannigan, Adrienne Michelle
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/26673