The reduction of tolerance to the anticonvulsant effects of antiepileptic drugs

Tolerance has been shown to develop to the anticonvulsant effects of many different antiepileptic drugs. In some cases, tolerance to antiepileptic drug effects is so complete that the drugs become clinically ineffective, even at toxic doses. This is clearly problematic for the treatment of epilepsy....

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Bibliographic Details
Main Author: Kalynchuk, Lisa E
Format: Others
Language:English
Published: 2008
Online Access:http://hdl.handle.net/2429/2546