The pharmacokinetics of metoclopramide in normal rats and in rats with experimental renal and hepatic dysfunction

The pharmacokinetics of metoclopramide in normal rats and in rats with experimental renal and hepatic dysfunction

Metoelopramide (MCP), 4 amino-5-chloro-2-methoxy-N(2-diethyl -aminoethyl) benzamide, a procainamide derivative, is a potent antiemetic and gastric motility modifier. Clinically, MCP is used in gastrointestinal diagnostic examinations, treatment of various types of gastrointestinal disorders and as a...

Full description

Bibliographic Details
Main Author:	Tam, Yun Kau
Language:	English
Published:	2010
Online Access:	http://hdl.handle.net/2429/23191

Similar Items

Hepatic first-pass metabolism of metoclopramide in the rat
by: Kapil, Ram Prakash
Published: (2010)

A sensitive GLC-ECD method for determination of metoclopramide in biological fluids
by: Tam, Yun Kau
Published: (2010)

Effect of Experimentally Induced Hepatic and Renal Failure on the Pharmacokinetics of Topiramate in Rats
by: Kamal M. Matar, et al.
Published: (2014-01-01)

Interaction of griseofulvin with metoclopramide, propantheline and phenobarbital in the rat
by: Jamali, Fakhredin
Published: (2010)

A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model
by: Yang Y, et al.
Published: (2018-12-01)

Metoclopramide disposition in normal and uremic humans
by: Wright, Matthew Rowland
Published: (2010)

Immunohistochemical Changes after Metoclopramide Administration in Rat Brain Cells
by: Seren Gülşen Gürgen, et al.
Published: (2018-12-01)

The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits
by: Cecilia Nwadiuto Amadi, et al.
Published: (2020-01-01)

Effects of Fuzheng Huayu recipe on entecavir pharmacokinetics in normal and dimethylnitrosamine-induced hepatic fibrosis rats
by: Tao Yang, et al.
Published: (2020-01-01)

The Effect of Concurrent Administration of Metoclopramide, Bromocriptine and Cumin Essential Oils on Rat Ovary
by: F Abbasi Hormozi, et al.
Published: (2016-07-01)

The pharmacokinetics of D-penicillamine in normal and adjuvant arthritic rats
by: Aird, Sheelagh Ann
Published: (1987)

Effects of acute moderate hypoxemia on the pharmacokinetics of metoclopramide and its metabolites in chronically instrumented sheep
by: Kim, John
Published: (2009)

Effects of acute moderate hypoxemia on the pharmacokinetics of metoclopramide and its metabolites in chronically instrumented sheep
by: Kim, John
Published: (2009)

Effects of Experimental Hyperlipidemia on the Pharmacokinetics of Tadalafil in Rats
by: Joo Hyun Lee, et al.
Published: (2012-10-01)

Positron Emission Tomography Imaging Reveals an Importance of Saturable Liver Uptake Transport for the Pharmacokinetics of Metoclopramide
by: Fabien Caillé, et al.
Published: (2018-01-01)

The neurotoxicity and pharmacokinetic study of tranexamic acid in renal failure rat
by: Yi-Ju Liao, et al.

PHARMACOKINETICS AND PHARMACODYNAMICS OF DRUGS IN PATIENTS WITH RENAL DYSFUNCTION
by: K. Zakon, et al.
Published: (2017-12-01)

Metoclopramide-induced akathisia
by: Gaurav Chauhan, et al.
Published: (2012-01-01)

Pharmacokinetics of galactose in normal subjects and patients with liver dysfunctions
by: Hu, Teh-Min, et al.
Published: (1993)

Altered Pharmacokinetics of Daunorubicin in Rats with CCl4-Induced Hepatic Injury
by: Min-Koo Choi, et al.
Published: (2007-09-01)

Effect of Disease State on the Pharmacokinetics of Bedaquiline in Renal-Impaired and Diabetic Rats
by: Abhishek Gour, et al.
Published: (2021-03-01)

The pharmacokinetics of sulfadimidine in the rat
by: Coates, Peter E.
Published: (2013)

The pharmacokinetics of sulfadimidine in the rat
by: Coates, Peter E.
Published: (2013)

Long-Term Saccharin Consumption and Increased Risk of Obesity, Diabetes, Hepatic Dysfunction, and Renal Impairment in Rats
by: Omar Hasan Azeez, et al.
Published: (2019-10-01)

Ketorolac pharmacokinetics in experimental cirrhosis by bile duct ligation in the rat
by: Liliana Rivera-Espinosa, PhD, et al.
Published: (2003-10-01)

Metoclopramide in schizophrenia (an open study).
by: Doongaji D, et al.
Published: (1986-07-01)

Metoclopramide-induced cardiac arrest
by: Martha M. Rumore, et al.
Published: (2011-11-01)

Clinical pharmacological studies on metoclopramide
by: Bateman, D. N.
Published: (1978)

Some aspects of the pharmacology of metoclopramide
by: Blower, Peter R.
Published: (1977)

Metoclopramide nanoparticles modulate immune response in a diabetic rat model: association with regulatory T cells and proinflammatory cytokines
by: Abd Ellah NH, et al.
Published: (2019-04-01)

Dichloromethane and ethanol co-exposure aggravates oxidative stress indices causing hepatic and renal dysfunction in pubertal rats.
by: Solomon E Owumi, et al.
Published: (2019-06-01)

Chaya (Jatropha tanjorensis) leafs protect against sodium benzoate mediated renal dysfunction and hepatic damage in rats
by: Johnson Olaleye Oladele, et al.
Published: (2020-03-01)

Pharmacokinetics of Two Alkaloids after Oral Administration of Rhizoma Coptidis Extract in Normal Rats and Irritable Bowel Syndrome Rats
by: Zipeng Gong, et al.
Published: (2014-01-01)

Pharmacokinetics of Indican and Its Effect on Methotrexate Pharmacokinetics in Rats
by: Shu-Ling Chan, et al.
Published: (2006)

Serum and hepatic nascent lipoproteins in normal and hypercholesterolemic rats.
by: P J Dolphin
Published: (1981-08-01)

Pharmacokinetics, hepatic extraction, and renal disposition of phosphorothioate oligodeoxynucleotides
by: Cho, Min-hee
Published: (2011)

Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats
by: Dong-Seok Lee, et al.
Published: (2018-04-01)

Pharmacokinetics of Tyrosol Metabolites in Rats
by: Da-Hye Lee, et al.
Published: (2016-01-01)

Pharmacokinetics of tea catechins in the rat.
Published: (2001)

The pharmacokinetics of saccharin in rat and man
by: Sweatman, T. W.
Published: (1981)