Chemical and biological studies of the radiosensitizer misonidazole

Misonidazole (Ro 07-0582) is a nitroheterocyclic drug which sensitizes hypoxic (oxygen-deficient) cells to the lethal action of ionising radiation. Tumours contain radioresistant hypoxic cells which may limit the usefulness of radiotherapy as a modality of cancer treatment. The use of misonidazole a...

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Bibliographic Details
Main Author: Josephy, P. David
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/2429/23060

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