Chemical and biological studies of the radiosensitizer misonidazole
Misonidazole (Ro 07-0582) is a nitroheterocyclic drug which sensitizes hypoxic (oxygen-deficient) cells to the lethal action of ionising radiation. Tumours contain radioresistant hypoxic cells which may limit the usefulness of radiotherapy as a modality of cancer treatment. The use of misonidazole a...
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Language: | English |
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2010
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Online Access: | http://hdl.handle.net/2429/23060 |