The role of adenosine 3’, 5’-monophosphate in the cardiac actions of glucagon

The biochemical and mechanical effects of glucagon were investigated in the isolated, perfused rat heart. Glucagon produced time and dose-dependent alteractions in myocardial force of contractions, glycogen phosphorylase activation and cyclic AMP accumulation. The positive inotropic effect was maxim...

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Bibliographic Details
Main Author: Brunt, Margaret Edna
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/19192