Studies of factors influencing drug efflux rates from liposomes and their impact on antitumor efficacy

The anti-tumor efficacy [i.e. anti-tumour efficacy] of liposomal formulations of cell cycle dependent anticancer drugs is dependent on the rates at which the drugs are released from the liposomes. Previous work on liposomal formulations of vincristine has shown increasing efficacy for formulations w...

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Bibliographic Details
Main Author: Johnston, Michael James Wilson
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18535