Hypoxia and rapamycin induced changes to the cell cycle of multicellular spheroids and human tumour xenografts leading to potential therapeutic advantage
The cell cycle is a tightly regulated process that is functioning optimally when all factors contribute at the precise time and level that is required. However, in tumours some of these pathways are malfunctioning and to study this, we are utilizing spheroids as our in vitro tumour model system. In...
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| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/2429/18496 |