The ABCs of antigen presentation : defining antigen processing pathways
The ATP-binding cassette (ABC) transporter TAP (ABCB2/3) is an integral component of the endogenous antigen processing pathway. Without TAP, antigenic peptides cannot enter the ER to bind to class I MHC molecules en route to the cell surface, and as a result, no cellmediated immune response can occu...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2009
|
| Online Access: | http://hdl.handle.net/2429/17320 |