Progress towards the asymmetric synthesis of nitiol : construction of the 1-hydroxy derivatives
The asymmetric synthesis of nitiol was proposed. We employed a convergent approach where the 12-membered B-ring was constructed at a late stage via the sequential coupling of two cyclopentane fragments. For the A-ring fragment, the initial stereochemistry was set using the Sharpless asymmetric e...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/17108 |