Optimization of the intracellular delivery properties of non-viral DNA carrier systems

A central problem faced by the gene therapy field is the lack of efficient non-toxic methods of delivery of DNA-based macromolecules, such as antisense oligonucleotides and plasmid DNA in vivo. A major reason for this is that currently available non-viral delivery systems are relatively inefficie...

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Bibliographic Details
Main Author: Sandhu, Ammen Preat
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/17064