Investigation of valproic acid-associated oxidative stress and hepatotoxicity
A serious adverse reaction of valproic acid (VPA), a widely used anti-epileptic, is a rare but potentially fatal hepatotoxicity affecting mostly children under 2 years of age with developmental delay and who are on VPA polytherapy. The mechanism of the hepatotoxicity remains unknown. This thesis des...
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Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/16903 |