Investigation of valproic acid-associated oxidative stress and hepatotoxicity

A serious adverse reaction of valproic acid (VPA), a widely used anti-epileptic, is a rare but potentially fatal hepatotoxicity affecting mostly children under 2 years of age with developmental delay and who are on VPA polytherapy. The mechanism of the hepatotoxicity remains unknown. This thesis des...

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Bibliographic Details
Main Author: Tong, Vincent
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/16903