Regulation of immunoproteasome expression by human brain endothelium : functional significance in MHC class I expression and CD8+ T cell adhesion to the cerebral endothelium
Brain inflammatory diseases are characterized by the entry of blood-borne leukocytes into the brain across the blood-brain barrier (BBB) that normally restricts their entry into the central nervous system. Recent studies indicate that infiltrating brain antigen-specific CD8+ T cells clonally expa...
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Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/16620 |