Regulation of immunoproteasome expression by human brain endothelium : functional significance in MHC class I expression and CD8+ T cell adhesion to the cerebral endothelium

Brain inflammatory diseases are characterized by the entry of blood-borne leukocytes into the brain across the blood-brain barrier (BBB) that normally restricts their entry into the central nervous system. Recent studies indicate that infiltrating brain antigen-specific CD8+ T cells clonally expa...

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Bibliographic Details
Main Author: Lau, Henry H. W.
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/16620