Endogenous glucagon-cells are necessary for the glucose-responsiveness of the HIT-T15 hamster β-cell line

The role of glucagon in glucose-stimulated insulin release was investigated using the hamster insulinoma cell line, HIT-T15, as a model of the pancreatic β-cell. Glucose-stimulated insulin release from HIT-T15 cells was concentration-dependent over a range of glucose concentrations between 0 and 15...

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Bibliographic Details
Main Author: Väänänen, Jeffrey Eric
Format: Others
Language:English
Published: 2008
Online Access:http://hdl.handle.net/2429/1513

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