The cell cycle phenotypes of polyhomeotic are due to loss of DNA damage checkpoints and are suppressed by the cohesin Pds5
The Polycomb group (PcG) are well known as epigenetic silencers of many target genes including important developmental regulators such as the Hox genes. PcG mutants also have mitotic phenotypes, though their cell cycle role is not understood. Depletion of the proximal isoform of the PcG protein Poly...
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| Format: | Others |
| Language: | English |
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University of British Columbia
2009
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| Online Access: | http://hdl.handle.net/2429/13385 |