Characterization of the role of p59Fyn in T cell development and anergy

Signaling via the T cell receptor (TCR) is essential for the development of thymocytes and the mounting of peripheral T cell responses. Studies of proximal TCR signaling have demonstrated that two kinases, Lck and Fyn, are involved in the initial TCR phosphorylation events that eventually lead to T...

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Bibliographic Details
Main Author: Utting, Oliver B.
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/13188