Dysregulation of integrin-linked kinase (ILK) signaling during colorectal carcinogenesis : modulation of signaling pathways by non-steroidal anti-inflammatory drugs (NSAID)
One of the most common events involved in the development of human colon cancer is the mutation of the adenomatous polyposis coli (APC) gene. This protein through its interactions with Axin and GSK3β, serves to regulate the cytosolic levels of β-catenin. Mutation of the APC gene, which impairs co...
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| Format: | Others |
| Language: | English |
| Published: |
2009
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| Online Access: | http://hdl.handle.net/2429/13101 |