Probing the interaction between huntingtin and NMDA receptors
Huntington's Disease (HD) is caused by an expansion (>35) of a polyglutamine (polyQ) tract, in the N-terminus of the protein, huntingtin (htt). Evidence suggests that the selective degeneration of striatal neurons seen in HD is, in part, caused by overactivation of N-methyl-D-aspartate (N...
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| Format: | Others |
| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/11765 |