The interactions among B2-glycoprotein I, natural anticoagulants, and complement : significance for the antiphospholipid syndrome

Antiphospholipid syndrome (APS) patients are predisposed to recurrent thrombosis and miscarriages. Elevated levels of complement activation have also been demonstrated. A major antigenic target of antiphospholipid autoantibodies (aPL) is β2- glycoprotein I (β2GPI). Impairments of anticoagulation...

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Bibliographic Details
Main Author: Sim, Derek Shu Kay
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10912

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