Isolation, identification and synthesis of hydromorphone metabolites : analysis and antinociceptive activities in comparison to morphine
As active drug metabolites may have profound pharmacological and toxicological effects on patients, a thorough understanding of the metabolic fate of the parent drug and the potential pharmacological and toxicological activities of its metabolite(s) is essential to the effective and safe usage of...
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Format: | Others |
Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/10145 |