Structure/function analysis of CD40; a key activator of B lymphocytes

B lymphocytes need two signals in order to differentiate into antibody-producing cells, one delivered by the B cell antigen receptor (BCR) and a second delivered by CD40. In the absence of the CD40 signal, B cells that receive only the BCR signal are rendered non-responsive or undergo apoptosis T...

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Bibliographic Details
Main Author: Sutherland, Claire Louise
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10033