| Summary: | 碩士 === 國立陽明大學 === 腦科學研究所 === 107 === Background: The study of the influence of past ambient temperature on human autonomic nerves did not specifically focus on the factor of weight, but also rarely explored the situation after a real sleep; or the study of autonomic nervous function or thermoregulation caused by overweight and obesity has not been specifically discussed about the cause of ambient temperature. In addition to constructing a link between subjective comfort and objective physiological changes in waking, this study explores the effects of ambient temperature on sleep, and subsequently increases the number of overweight subjects, thereby exploring the more comprehensive consideration of ambient temperature for the impact of comfort and objective physiological changes by different body groups. The experiment is divided into two parts. The first part is to measure the effects of different temperatures on autonomic nerve function, brain wave and subjective feeling under awake; the second part is to explore the temperature tested in the first stage and the effect on sleep quality. Material and Methods: The subjects recruited in this experiment were divided into two groups, and the control groupwith normal BMI and overweight group. Subjects will use the miniature polysomnography, developed by the K&Y lab to record the EEG, EMG and ECG signals of the subjects, and analyze brain wave spectrum and autonomic nervous function by Fast Fourier Transform (FFT). In the first stage of the experiment, the subjects remained awake, and the subjects were asked to respond to subjective feelings at different temperatures , and the physiological signals were recorded. In the second stage of the experiment, the subjects will fall asleep at eight different temperatures for eight nights. The experimental temperatures were the same as that of the first stage, and the miniature polysomnography was used to record the physiological parameters, and the subjects were asked to reply sleep feeling before going to bed and after getting up. Results: Compared with normal body weight in awake or sleep stage, the overweight sympathetic nerve activity is relatively low, sympathetic nerve activity is relatively high, and prefer low temperature. LF/HF and LF% cardiac sympathetic nerve activity of overweight increases with the increase or decrease of temperature to form a U-shaped distribution, which can be used as a physiological indicator of temperature perception during waking. Through HF parasympathetic activity during sleep and LF/HF and LF% cardiac sympathetic activity, it was found that overweight had better objective sleep quality at cold environment. The HF parasympathetic activity and LF/HF and LF% cardiac sympathetic activity of the first stage of sleep can also be used as an objective physiological indicator of body weight for sleep at different temperatures. The part of the brain wave can refer to beta and alpha waves as objective indicators of sensation of temperature and temperature perception during sleep. Sleep onset, first and third sleep stage and ratio can be used as objective indicators of the effect of body weight on different temperature sleep structures. Conclusions: Compared with normal weight in awake or sleep stage, the parasympathetic nerve activity of overweight is relatively low, the sympathetic nerve activity is relatively high, and the subjective and objective comfort prefers a lower temperature, and the optimal comfort temperature is 22 °C. Ambient temperature affects sleep quality, and sleep quality is affected by autonomic nerves and body temperature. This study also proves that body weight does affect subjective and autonomic functions. The subjective and objective physiological indicators of temperature perception of different body weights will also be different. So body weight is an important factor that affects the feeling of sleep and temperature.
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