| Summary: | 碩士 === 慈濟大學 === 公共衛生學系碩士班 === 107 === ABSTRACT
Background: Tuberculosis is a challenging issue in the world especially the public health field. Recurrent pulmonary tuberculosis (PTB) continues to be a significant problem and is an important indicator of the effectiveness of TB control. There is a lack of resources and no special attention is being given to identify risk factors for recurrent tuberculosis in Mongolia. Nowadays it is not clear that outdoor air pollution influences on development of tuberculosis in Mongolia. The aim of this study was to investigate the relationship between the outdoor air pollution and prevalence, incidence and mortality rates of PTB and to identify risk factors for recurrent PTB in Ulaanbaatar (UB), Mongolia.
Material and Methods: In ecological study, we collected air pollution levels from ten monitor stations in six districts of UB from National Agency for Meteorology, Hydrology and Environmental Monitoring and National Air Quality Council of Mongolia. In retrospective case control study (2012 to 2016), demographic, clinical, environmental factors were analyzed. The data were collected from Surveillance and Research Department of The National Center for Communicable Disease of Mongolia. Simple linear regression, univariate and multivariate logistic regression analyses were performed using SPSS.22.
Results: We didn’t find any significant association between air pollutants and PTB disease burden in six districts, UB, Mongolia. But we found that SO2 level was statistically significant associated with the incidence and prevalence of PTB (Pearson correlation coefficient = 0.98, 0.97, respectively) among five districts (except Khan-Uul district). Compared to Bayangol district which had lower levels of PM10 and SO2, the other five districts had statistically higher incidence and prevalence of PTB. Patients whose age was older than 34 years old, (OR= 1.70; 95%CI: 1.11- 2.62) and who had co-morbidities (OR= 3.4; 95% CI: 2.03-5.88) particularly, diabetes mellitus (OR=5.94; 95% CI: 3.09-11.40) had significantly increased risk for recurrent PTB.
Conclusions: We found that SO2 or socioeconomic difference might play a role in the PTB burden and having co-morbidities and getting older increased risk for recurrent PTB.
Keyword: Pulmonary Tuberculosis; Risk factor, Recurrence Tuberculosis; Outdoor Air Pollution.
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