| Summary: | 碩士 === 國立臺灣大學 === 臨床動物醫學研究所 === 107 === Blood pressure is one of the vital signs in clinical medicine, its’ reading provides a direct evaluation of systemic circulation. However, in birds, blood pressure measurement is not performed routinely during physical examination owing to special physiologic, anatomic limitations and inaccuracy of indirect blood pressure measurement in avian patients. Intraosseous catheter is now the most commonly used route in avian fluid therapy, especially for those small sized or are hypotensive that makes the vessel inaccessible. In human medicine, similar limitations were encountered in neonatal or critically illed patients, some research has found that intraosseous catheter can be placed more quickly, easily, and with lower complications. Hence, recently, more and more researches has focused on the relationship between intraosseous pressure and arterial pressure, and try to find if the intraosseous pressure measurement could replace blood pressure measurement in clinical condition
In this study, we used 12 healthy sub-adult or adult African grey parrots (Psittacus erithacus) as experimental subjects. Each bird was maintained under general anesthesia condition, a 24 gauge catheter was installed into the deep radial artery and a 22 guage needle was installed into the ulna medullary cavity respectively. Both catheters connected to a disposable pressure sensor, and arterial pressure waveform and intraosseous pressure waveforms were recorded for 10 minutes. The arterial pressure values were normally distributed while the intraosseous pressure values were not. The average of arterial systolic, mean, diastolic pressure values are 118.90±11.66(94.50-136.02) mmHg, 94.86±17.97(66.89-129.51) mmHg and 79.66±20.42(49.05-117.87) mmHg. The average of intraosseous mean pressure values is 49.17± 29.94(2.03-93.21) mmHg, and the average heart rate is 315.19± 101.14(158.20-490.60) beat per minute. There’s no correlation between arterial pressure values and intraosseous pressure values. A positive relationship between heart rate and mean intraosseous pressure values was found and the correlation coefficient was 0.58.
Though future research may need to determine the efficacy of intraosseous pressure, based on its easier and less time consuming techniques, it is still a potential method for further clinical use in avian patients.
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