Antitumor Effect and Immunity Generated by Antigen-Specific DNA Vaccine Are Enhanced by Immune Checkpoint Blockade
博士 === 國立臺灣大學 === 腫瘤醫學研究所 === 107 === I determined the antitumor effects and possible mechanisms of an antigen-specific DNA vaccine combined with PD-1 or CTLA-4 blockade. Using the HPV16 E6/E7+ syngeneic mouse tumor model, we investigated whether anti-CTLA-4 antibody (Ab) or anti-PD-1 Ab increases t...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2019
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| Online Access: | http://ndltd.ncl.edu.tw/handle/cnu6u6 |