A novel stem-cell-embedded wound healing patch fabricated by photopolymerization 3D printing

• Main Authors: JUI-KANG KUO, 郭瑞崗
• Other Authors: Poling-Kuo
• Format: Others
• Language: en_US
• Published: 2019
• Online Access: http://ndltd.ncl.edu.tw/handle/t5c5jm

碩士 === 國立臺灣大學 === 生醫電子與資訊學研究所 === 107 === Mesenchymal stem cells (MSCs) have been shown to be potential candidates to cell therapy due to their immunomodulation and regeneration abilities. Lots of clinical trials have reached successful results that MSCs could enhance the wound healing process. However, the mechanism how MSCs affect the process and what is the most efficient way to apply cells to the wound still need to be investigated. Some novel cell-embedded patches are introduced in this study to keep the cells at the wound site. The GelMA-based wound healing patch can be fabricated on customization to any shape to meet the clinical needs through 3D printing technique. Most of the cells could survive for more than 12hrs under proper condition, which made the patch a promising product for clinical use in the near future.