| Summary: | 碩士 === 南開科技大學 === 福祉科技與服務管理所 === 107 === In recent years, there has been an increase in the proportion of patients who opted to sign the Do Not Resuscitate （DNR）/Do Not Intubate （DNR）oders and were given Non-Invasive Ventilation（NIV）.In particular, NIV has been relatively widely used in DNI patients with reversible acute respiratory failure.There are many overseas studies on the clinical applications or ethical issues of NIV. However, there are very few relevant studies in Taiwan. Therefore, the aimog this study is to investigate the NIV effectiveness in DNI patients with acute respiratory failure in a district hospital in Taiwan. We retrospectively analyed the medical records of 349 DNI patients who were admitted to the intensive care unit due to acute respiratory failure and were administered NIV from June 2014 to June 2017. Cross-analysis of the study results found that the success rate is higher for patients, from long-term care institutions, patients with low respiratory rate and higher diastolic blood pressure, and patients with increased PH and PaO2 after NIV use for 48 hours, and these differences are statistically significant. Logistic regression analysis found that patients with a Glasgow Coma Scale（GCS）≦8 points have a higher mortality rate than those with a GCS score of ＞8 points and this is significant（odds ratio:2.83; confidence interval:1.68-1.81）.With regards to disease category, category, cancer motality rate was the highest compared with Chronic Obstructive Pulmonary Disease（COPD）and this is significant（odds ratio:13.6; confidence interval:2.57-71.84）. Based on the results of this study, the survival success rate is increased when NIV is used for DNI patients with acute respiratory failure in the ICU. This data can be an important reference for counseling DNI patients and their family members on whether NIV should be used in clinical practice.
Keywords: Acute respiratory failure, Do not intubate, Non-invasive ventilation
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